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Differential Survival and Therapy Benefit of Patients with Breast Cancer Are Characterized by Distinct Epithelial and Immune Cell Microenvironments

PURPOSE: Extensive work in preclinical models has shown that microenvironmental cells influence many aspects of cancer cell behavior, including metastatic potential and their sensitivity to therapeutics. In the human setting, this behavior is mainly correlated with the presence of immune cells. Here...

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Detalles Bibliográficos
Autores principales: Kester, Lennart, Seinstra, Danielle, van Rossum, Annelot G.J., Vennin, Claire, Hoogstraat, Marlous, van der Velden, Daphne, Opdam, Mark, van Werkhoven, Erik, Hahn, Kerstin, Nederlof, Iris, Lips, Ester H., Mandjes, Ingrid A.M., van Leeuwen-Stok, A. Elise, Canisius, Sander, van Tinteren, Harm, Imholz, Alex L.T., Portielje, Johanneke E.A., Bos, Monique E.M.M., Bakker, Sandra D., Rutgers, Emiel J., Horlings, Hugo M., Wesseling, Jelle, Voest, Emile E., Wessels, Lodewyk F.A., Kok, Marleen, Oosterkamp, Hendrika M., van Oudenaarden, Alexander, Linn, Sabine C., van Rheenen, Jacco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377758/
https://www.ncbi.nlm.nih.gov/pubmed/34965952
http://dx.doi.org/10.1158/1078-0432.CCR-21-1442