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Anlotinib Induces a T Cell–Inflamed Tumor Microenvironment by Facilitating Vessel Normalization and Enhances the Efficacy of PD-1 Checkpoint Blockade in Neuroblastoma

PURPOSE: Anlotinib has achieved good results in clinical trials of a variety of cancers. However, the effects of anlotinib on the tumor microenvironment (TME) and systemic immunity have not been reported. There is an urgent need to identify the underlying mechanism to reveal new opportunities for it...

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Detalles Bibliográficos
Autores principales: Su, Yudong, Luo, Bingying, Lu, Yao, Wang, Daowei, Yan, Jie, Zheng, Jian, Xiao, Jun, Wang, Yangyang, Xue, Zhenyi, Yin, Jie, Chen, Peng, Li, Long, Zhao, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377760/
https://www.ncbi.nlm.nih.gov/pubmed/34844980
http://dx.doi.org/10.1158/1078-0432.CCR-21-2241