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Anlotinib Induces a T Cell–Inflamed Tumor Microenvironment by Facilitating Vessel Normalization and Enhances the Efficacy of PD-1 Checkpoint Blockade in Neuroblastoma
PURPOSE: Anlotinib has achieved good results in clinical trials of a variety of cancers. However, the effects of anlotinib on the tumor microenvironment (TME) and systemic immunity have not been reported. There is an urgent need to identify the underlying mechanism to reveal new opportunities for it...
Autores principales: | Su, Yudong, Luo, Bingying, Lu, Yao, Wang, Daowei, Yan, Jie, Zheng, Jian, Xiao, Jun, Wang, Yangyang, Xue, Zhenyi, Yin, Jie, Chen, Peng, Li, Long, Zhao, Qiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377760/ https://www.ncbi.nlm.nih.gov/pubmed/34844980 http://dx.doi.org/10.1158/1078-0432.CCR-21-2241 |
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