The Pan-Tumor Landscape of Targetable Kinase Fusions in Circulating Tumor DNA

PURPOSE: Oncogenic kinase fusions are targetable with approved and investigational therapies and can also mediate acquired resistance (AR) to targeted therapy. We aimed to understand the clinical validity of liquid biopsy comprehensive genomic profiling (CGP) to detect kinase fusions pan tumor. EXPE...

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Detalles Bibliográficos
Autores principales: Lee, Jessica K., Hazar-Rethinam, Mehlika, Decker, Brennan, Gjoerup, Ole, Madison, Russell W., Lieber, Daniel S., Chung, Jon H., Schrock, Alexa B., Creeden, James, Venstrom, Jeffrey, Alexander, Brian, Oxnard, Geoffrey R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Precision Medicine and Imaging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377769/
https://www.ncbi.nlm.nih.gov/pubmed/34753780
http://dx.doi.org/10.1158/1078-0432.CCR-21-2136

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377769/
https://www.ncbi.nlm.nih.gov/pubmed/34753780
http://dx.doi.org/10.1158/1078-0432.CCR-21-2136

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