TRPV1 drugs alter core body temperature via central projections of primary afferent sensory neurons

TRPV1, a capsaicin- and heat-activated ion channel, is expressed by peripheral nociceptors and has been implicated in various inflammatory and neuropathic pain conditions. Although pharmacological modulation of TRPV1 has attracted therapeutic interest, many TRPV1 agonists and antagonists produce the...

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Detalles Bibliográficos
Autores principales: Yue, Wendy Wing Sze, Yuan, Lin, Braz, Joao M, Basbaum, Allan I, Julius, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377796/
https://www.ncbi.nlm.nih.gov/pubmed/35968676
http://dx.doi.org/10.7554/eLife.80139

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377796/
https://www.ncbi.nlm.nih.gov/pubmed/35968676
http://dx.doi.org/10.7554/eLife.80139

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