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TRPV1 drugs alter core body temperature via central projections of primary afferent sensory neurons
TRPV1, a capsaicin- and heat-activated ion channel, is expressed by peripheral nociceptors and has been implicated in various inflammatory and neuropathic pain conditions. Although pharmacological modulation of TRPV1 has attracted therapeutic interest, many TRPV1 agonists and antagonists produce the...
Autores principales: | Yue, Wendy Wing Sze, Yuan, Lin, Braz, Joao M, Basbaum, Allan I, Julius, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377796/ https://www.ncbi.nlm.nih.gov/pubmed/35968676 http://dx.doi.org/10.7554/eLife.80139 |
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