Intracellular ATP Signaling Contributes to FAM3A-Induced PDX1 Upregulation in Pancreatic Beta Cells

FAM3A is a recently identified mitochondrial protein that stimulates pancreatic-duodenal homeobox 1 (PDX1) and insulin expressions by promoting ATP release in islet β cells. In this study, the role of intracellular ATP in FAM3A-induced PDX1 expression in pancreatic β cells was further examined. Acut...

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Detalles Bibliográficos
Autores principales: Yan, Han, Chen, Zhenzhen, Zhang, Haizeng, Yang, Weili, Liu, Xiangyang, Meng, Yuhong, Xiang, Rui, Wu, Zhe, Ye, Jingjing, Chi, Yujing, Yang, Jichun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377833/
https://www.ncbi.nlm.nih.gov/pubmed/34592773
http://dx.doi.org/10.1055/a-1608-0607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377833/
https://www.ncbi.nlm.nih.gov/pubmed/34592773
http://dx.doi.org/10.1055/a-1608-0607

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