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Aloe-Emodin Suppresses Oxidative Stress and Inflammation via a PI3K-Dependent Mechanism in a Murine Model of Sepsis

BACKGROUND: This study was designed to assess the impact of aloe-emodin (AE) on oxidative stress and inflammation in a murine model of LPS-induced sepsis. In addition, the mechanistic basis for anti-inflammatory and antioxidant activity was assessed. METHODS: Male ICR mice received an intraperitonea...

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Detalles Bibliográficos
Autores principales: Gao, Huijie, Ren, Yan, Liu, Chao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377882/
https://www.ncbi.nlm.nih.gov/pubmed/35978995
http://dx.doi.org/10.1155/2022/9697887