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Melatonin Alleviates Acute Kidney Injury by Inhibiting NRF2/Slc7a11 Axis-Mediated Ferroptosis

Acute kidney injury (AKI) is still a puzzling clinical problem; its pathophysiology is not completely understood. Up to now, an effective treatment for AKI is lacking. Ferroptosis is a novel form of regulated cell death characterized by the lethal accumulation of lipid hydroperoxides that are depend...

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Detalles Bibliográficos
Autores principales: Huang, Yue-bo, Jiang, Ling, Liu, Xue-qi, Wang, Xian, Gao, Li, Zeng, Han-xu, Zhu, Wei, Hu, Xue-ru, Wu, Yong-gui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9377938/
https://www.ncbi.nlm.nih.gov/pubmed/35979396
http://dx.doi.org/10.1155/2022/4776243