Targeting MYC and BCL2 by a natural compound for “double‐hit” lymphoma

Concurrent translocations of MYC and BCL2 lead to abnormal expression of both oncoproteins, which contribute to the aggressive clinical characteristics of double‐hit lymphoma (DHL). An effective therapy for DHL remains an unmet clinical need. In this study, we showed that both Ca(2+)/calmodulin‐depe...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xiaoqian, Xu, Senlin, Zhang, Jiawei, Fan, Mingjie, Xie, Jun, Zhang, Bingfeng, Li, Hongzhi, Yu, Guohua, Liu, Yinghui, Zhang, Yuanfeng, Song, Joo, Horne, David, Chan, Wing C., Chu, Xiaoxia, Huang, Wendong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378491/
https://www.ncbi.nlm.nih.gov/pubmed/35482553
http://dx.doi.org/10.1002/hon.3010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378491/
https://www.ncbi.nlm.nih.gov/pubmed/35482553
http://dx.doi.org/10.1002/hon.3010

Ejemplares similares