Chimeric GPCRs mimic distinct signaling pathways and modulate microglia responses

G protein-coupled receptors (GPCRs) regulate processes ranging from immune responses to neuronal signaling. However, ligands for many GPCRs remain unknown, suffer from off-target effects or have poor bioavailability. Additionally, dissecting cell type-specific responses is challenging when the same...

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Detalles Bibliográficos
Autores principales: Schulz, Rouven, Korkut-Demirbaş, Medina, Venturino, Alessandro, Colombo, Gloria, Siegert, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378622/
https://www.ncbi.nlm.nih.gov/pubmed/35970889
http://dx.doi.org/10.1038/s41467-022-32390-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378622/
https://www.ncbi.nlm.nih.gov/pubmed/35970889
http://dx.doi.org/10.1038/s41467-022-32390-1

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