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Single-cell transcriptomic profiling unveils dysregulation of cardiac progenitor cells and cardiomyocytes in a mouse model of maternal hyperglycemia

Congenital heart disease (CHD) is the most prevalent birth defect, often linked to genetic variations, environmental exposures, or combination of both. Epidemiological studies reveal that maternal pregestational diabetes is associated with ~5-fold higher risk of CHD in the offspring; however, the ca...

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Detalles Bibliográficos
Autores principales: Manivannan, Sathiyanarayanan, Mansfield, Corrin, Zhang, Xinmin, Kodigepalli, Karthik M., Majumdar, Uddalak, Garg, Vidu, Basu, Madhumita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378651/
https://www.ncbi.nlm.nih.gov/pubmed/35970860
http://dx.doi.org/10.1038/s42003-022-03779-x