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Single-cell transcriptomic profiling unveils dysregulation of cardiac progenitor cells and cardiomyocytes in a mouse model of maternal hyperglycemia
Congenital heart disease (CHD) is the most prevalent birth defect, often linked to genetic variations, environmental exposures, or combination of both. Epidemiological studies reveal that maternal pregestational diabetes is associated with ~5-fold higher risk of CHD in the offspring; however, the ca...
Autores principales: | Manivannan, Sathiyanarayanan, Mansfield, Corrin, Zhang, Xinmin, Kodigepalli, Karthik M., Majumdar, Uddalak, Garg, Vidu, Basu, Madhumita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378651/ https://www.ncbi.nlm.nih.gov/pubmed/35970860 http://dx.doi.org/10.1038/s42003-022-03779-x |
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