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A GLP1 receptor agonist diabetes drug ameliorates neurodegeneration in a mouse model of infantile neurometabolic disease

Infantile neuroaxonal dystrophy (INAD) is a rare paediatric neurodegenerative condition caused by mutations in the PLA2G6 gene, which is also the causative gene for PARK14-linked young adult-onset dystonia parkinsonism. INAD patients usually die within their first decade of life, and there are curre...

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Detalles Bibliográficos
Autores principales: Poupon-Bejuit, L., Hughes, M. P., Liu, W., Geard, A., Faour-Slika, N., Whaler, S., Massaro, G., Rahim, A. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378686/
https://www.ncbi.nlm.nih.gov/pubmed/35970890
http://dx.doi.org/10.1038/s41598-022-17338-1