Cargando…
A GLP1 receptor agonist diabetes drug ameliorates neurodegeneration in a mouse model of infantile neurometabolic disease
Infantile neuroaxonal dystrophy (INAD) is a rare paediatric neurodegenerative condition caused by mutations in the PLA2G6 gene, which is also the causative gene for PARK14-linked young adult-onset dystonia parkinsonism. INAD patients usually die within their first decade of life, and there are curre...
Autores principales: | Poupon-Bejuit, L., Hughes, M. P., Liu, W., Geard, A., Faour-Slika, N., Whaler, S., Massaro, G., Rahim, A. A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378686/ https://www.ncbi.nlm.nih.gov/pubmed/35970890 http://dx.doi.org/10.1038/s41598-022-17338-1 |
Ejemplares similares
-
GLP-1 Receptor Agonists in Neurodegeneration: Neurovascular Unit in the Spotlight
por: Monti, Giulia, et al.
Publicado: (2022) -
A Novel Small NPC1 Promoter Enhances AAV-Mediated Gene Therapy in Mouse Models of Niemann–Pick Type C1 Disease
por: Hughes, Michael Paul, et al.
Publicado: (2023) -
Neuroprotective Effects of Diabetes Drugs for the Treatment of Neonatal Hypoxia-Ischemia Encephalopathy
por: Poupon-Bejuit, Laura, et al.
Publicado: (2020) -
Targeting redox imbalance in neurodegeneration: characterizing the role of GLP-1 receptor agonists
por: Ghosh, Puja, et al.
Publicado: (2023) -
An Approach to Neurometabolic Epilepsy in Children with an Underlying Neurometabolic Disorder
por: KARIMZADEH, Parvaneh, et al.
Publicado: (2020)