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SH3 domain regulation of RhoGAP activity: Crosstalk between p120RasGAP and DLC1 RhoGAP

RhoGAP proteins are key regulators of Rho family GTPases and influence a variety of cellular processes, including cell migration, adhesion, and cytokinesis. These GTPase activating proteins (GAPs) downregulate Rho signaling by binding and enhancing the intrinsic GTPase activity of Rho proteins. Dele...

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Detalles Bibliográficos
Autores principales: Chau, Jocelyn E., Vish, Kimberly J., Boggon, Titus J., Stiegler, Amy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378701/
https://www.ncbi.nlm.nih.gov/pubmed/35970859
http://dx.doi.org/10.1038/s41467-022-32541-4