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GPCR/endocytosis/ERK signaling/S2R is involved in the regulation of the internalization, mitochondria-targeting and -activating properties of human salivary histatin 1

Human salivary histatin 1 (Hst1) exhibits a series of cell-activating properties, such as promoting cell spreading, migration, and metabolic activity. We recently have shown that fluorescently labeled Hst1 (F-Hst1) targets and activates mitochondria, presenting an important molecular mechanism. Howe...

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Detalles Bibliográficos
Autores principales: Ma, Dandan, Sun, Wei, Fu, Cuicui, Nazmi, Kamran, Veerman, Enno C. I., Jaspers, Richard T., Bolscher, Jan G. M., Bikker, Floris J., Wu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378733/
https://www.ncbi.nlm.nih.gov/pubmed/35970844
http://dx.doi.org/10.1038/s41368-022-00181-5