Loss of Nexmif results in the expression of phenotypic variability and loss of genomic integrity

We identified two NEXMIF variants in two unrelated individuals with non-autoimmune diabetes and autistic traits, and investigated the expression of Nexmif in mouse and human pancreas and its function in pancreatic beta cells in vitro and in vivo. In insulin-secreting INS-1E cells, Nexmif expression...

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Detalles Bibliográficos
Autores principales: Stekelenburg, Caroline, Blouin, Jean-Louis, Santoni, Federico, Zaghloul, Norann, O’Hare, Elisabeth A., Dusaulcy, Rodolphe, Maechler, Pierre, Schwitzgebel, Valerie M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378738/
https://www.ncbi.nlm.nih.gov/pubmed/35970867
http://dx.doi.org/10.1038/s41598-022-17845-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378738/
https://www.ncbi.nlm.nih.gov/pubmed/35970867
http://dx.doi.org/10.1038/s41598-022-17845-1

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