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Dynamically upregulated mast cell CPA3 patterns in chronic obstructive pulmonary disease and idiopathic pulmonary fibrosis

BACKGROUND: The mast cell-specific metalloprotease CPA3 has been given important roles in lung tissue homeostasis and disease pathogenesis. However, the dynamics and spatial distribution of mast cell CPA3 expression in lung diseases remain unknown. METHODS: Using a histology-based approach for quant...

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Detalles Bibliográficos
Autores principales: Siddhuraj, Premkumar, Jönsson, Jimmie, Alyamani, Manar, Prabhala, Pavan, Magnusson, Mattias, Lindstedt, Sandra, Erjefält, Jonas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378779/
https://www.ncbi.nlm.nih.gov/pubmed/35983043
http://dx.doi.org/10.3389/fimmu.2022.924244