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Patient-Derived Organoid Facilitating Personalized Medicine in Gastrointestinal Stromal Tumor With Liver Metastasis: A Case Report

The gastrointestinal stromal tumors (GIST) are a rare gastrointestinal tract malignancy. The two primary mutation sites are found in KIT and platelet-derived growth factor receptor-α (PDGFR-α) genes. The current study reports on a point mutation within the exon 11 of KIT, named KIT p.V560E. Patient-...

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Detalles Bibliográficos
Autores principales: Cao, Ying, Zhang, Xi, Chen, Qianyun, Rao, Xi, Qiu, Enming, Wu, Gang, Lin, Yu, Zeng, Ziqi, Zheng, Bin, Li, Zhou, Cai, Zhai, Wang, Huaiming, Han, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9378866/
https://www.ncbi.nlm.nih.gov/pubmed/35982969
http://dx.doi.org/10.3389/fonc.2022.920762