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Validation and clinical application of a method to quantify efavirenz in cervicovaginal secretions from flocked swabs using liquid chromatography tandem mass spectrometry

Background : A liquid chromatography tandem mass spectrometry method to quantify drugs in dried cervicovaginal secretions from flocked swabs was developed and validated using the antiretroviral efavirenz as an example. Methods: Cervicovaginal swabs (CVS) were prepared by submerging flocked swabs in...

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Detalles Bibliográficos
Autores principales: Olagunju, Adeniyi, Nwogu, Jacinta, Eniayewu, Oluwasegun, Atoyebi, Shakir, Amara, Alieu, Kpamor, John, Bolaji, Oluseye, Adejuyigbe, Ebunoluwa, Owen, Andrew, Khoo, Saye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379332/
https://www.ncbi.nlm.nih.gov/pubmed/36034058
http://dx.doi.org/10.12688/wellcomeopenres.17202.3