CpG content in the Zika virus genome affects infection phenotypes in the adult brain and fetal lymph nodes

Increasing the number of CpG dinucleotides in RNA viral genomes, while preserving the original amino acid composition, leads to impaired infection which does not cause disease. Beneficially, impaired infection evokes antiviral host immune responses providing a cutting-edge vaccine approach. For exam...

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Detalles Bibliográficos
Autores principales: Udenze, Daniel, Trus, Ivan, Berube, Nathalie, Karniychuk, Uladzimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379343/
https://www.ncbi.nlm.nih.gov/pubmed/35983032
http://dx.doi.org/10.3389/fimmu.2022.943481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379343/
https://www.ncbi.nlm.nih.gov/pubmed/35983032
http://dx.doi.org/10.3389/fimmu.2022.943481

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