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CpG content in the Zika virus genome affects infection phenotypes in the adult brain and fetal lymph nodes
Increasing the number of CpG dinucleotides in RNA viral genomes, while preserving the original amino acid composition, leads to impaired infection which does not cause disease. Beneficially, impaired infection evokes antiviral host immune responses providing a cutting-edge vaccine approach. For exam...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379343/ https://www.ncbi.nlm.nih.gov/pubmed/35983032 http://dx.doi.org/10.3389/fimmu.2022.943481 |