The Interaction of SWI/SNF with the Ribosome Regulates Translation and Confers Sensitivity to Translation Pathway Inhibitors in Cancers with Complex Perturbations

Subunits from the chromatin remodelers mammalian SWItch/Sucrose Non-Fermentable (mSWI/SNF) are mutated, deleted, or amplified in more than 40% of cancers. Understanding their functions in normal cells and the consequences of cancerous alterations will provide insight into developing new targeted the...

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Detalles Bibliográficos
Autores principales: Ulicna, Livia, Kimmey, Samuel C., Weber, Christopher M., Allard, Grace M., Wang, Aihui, Bui, Nam Q., Bendall, Sean C., Crabtree, Gerald R., Bean, Gregory R., Van Rechem, Capucine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Priority Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379364/
https://www.ncbi.nlm.nih.gov/pubmed/35749589
http://dx.doi.org/10.1158/0008-5472.CAN-21-1360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379364/
https://www.ncbi.nlm.nih.gov/pubmed/35749589
http://dx.doi.org/10.1158/0008-5472.CAN-21-1360

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