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Platelet-derived microRNA-223 attenuates TNF-α induced monocytes adhesion to arterial endothelium by targeting ICAM-1 in Kawasaki disease

BACKGROUND: Kawasaki disease (KD) is an acute vasculitis that may result in permanent coronary artery damage with unknown etiology. Endothelial cell (EC) dysfunction and platelet hyperactivity are the hallmarks of KD. Platelets are involved in the development of endothelial dysfunction. MiR-223 tran...

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Detalles Bibliográficos
Autores principales: Guo, Manli, Fan, Shunyang, Chen, Qian, Jia, Cuiping, Qiu, Miaoyun, Bu, Yun, Tang, Wai Ho, Zhang, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379370/
https://www.ncbi.nlm.nih.gov/pubmed/35983051
http://dx.doi.org/10.3389/fimmu.2022.922868