Aberrant splicing events caused by insertion of genes of interest into expression vectors

Background: Expression of genes of interest from plasmids or lentiviral vectors is one of the most common tools in molecular and gene therapy. Aberrant splicing between the inserted gene of interest and downstream vector sequence has not been systematically analyzed. Methods: Formation of aberrant f...

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Detalles Bibliográficos
Autores principales: Cheng, Yun, Kang, Xiao-Zhuo, Chan, Pearl, Ye, Zi-Wei, Chan, Chi-Ping, Jin, Dong-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379414/
https://www.ncbi.nlm.nih.gov/pubmed/35982889
http://dx.doi.org/10.7150/ijbs.72408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379414/
https://www.ncbi.nlm.nih.gov/pubmed/35982889
http://dx.doi.org/10.7150/ijbs.72408

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