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Aberrant splicing events caused by insertion of genes of interest into expression vectors
Background: Expression of genes of interest from plasmids or lentiviral vectors is one of the most common tools in molecular and gene therapy. Aberrant splicing between the inserted gene of interest and downstream vector sequence has not been systematically analyzed. Methods: Formation of aberrant f...
Autores principales: | Cheng, Yun, Kang, Xiao-Zhuo, Chan, Pearl, Ye, Zi-Wei, Chan, Chi-Ping, Jin, Dong-Yan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379414/ https://www.ncbi.nlm.nih.gov/pubmed/35982889 http://dx.doi.org/10.7150/ijbs.72408 |
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