Investigating the roles of hyperglycaemia, hyperinsulinaemia and elevated free fatty acids in cardiac function in patients with type 2 diabetes via treatment with insulin compared with empagliflozin: protocol for the HyperCarD2 randomised, crossover trial

INTRODUCTION: Type 2 diabetes (T2D) is characterised by elevated plasma glucose, free fatty acid (FFA) and insulin concentrations, and this metabolic profile is linked to diabetic cardiomyopathy, a diastolic dysfunction at first and increased cardiovascular disease (CVD) risk. Shifting cardiac metab...

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Detalles Bibliográficos
Autores principales: Thirumathyam, Roopameera, Richter, Erik Arne, Goetze, Jens Peter, Fenger, Mogens, Van Hall, Gerrit, Dixen, Ulrik, Holst, Jens Juul, Madsbad, Sten, Vejlstrup, Niels, Madsen, Per Lav, Jørgensen, Nils Bruun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Cardiovascular Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379482/
https://www.ncbi.nlm.nih.gov/pubmed/35953245
http://dx.doi.org/10.1136/bmjopen-2021-054100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379482/
https://www.ncbi.nlm.nih.gov/pubmed/35953245
http://dx.doi.org/10.1136/bmjopen-2021-054100

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