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Investigating the roles of hyperglycaemia, hyperinsulinaemia and elevated free fatty acids in cardiac function in patients with type 2 diabetes via treatment with insulin compared with empagliflozin: protocol for the HyperCarD2 randomised, crossover trial
INTRODUCTION: Type 2 diabetes (T2D) is characterised by elevated plasma glucose, free fatty acid (FFA) and insulin concentrations, and this metabolic profile is linked to diabetic cardiomyopathy, a diastolic dysfunction at first and increased cardiovascular disease (CVD) risk. Shifting cardiac metab...
Autores principales: | Thirumathyam, Roopameera, Richter, Erik Arne, Goetze, Jens Peter, Fenger, Mogens, Van Hall, Gerrit, Dixen, Ulrik, Holst, Jens Juul, Madsbad, Sten, Vejlstrup, Niels, Madsen, Per Lav, Jørgensen, Nils Bruun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379482/ https://www.ncbi.nlm.nih.gov/pubmed/35953245 http://dx.doi.org/10.1136/bmjopen-2021-054100 |
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