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Data of transcriptional effects of the merbarone-mediated inhibition of TOP2

Type II DNA topoisomerases relax topological stress by transiently gating DNA passage in a controlled cut-and-reseal mechanism that affects both DNA strands. Therefore, they are essential to overcome topological problems associated with DNA metabolism. Their aberrant activity results in the generati...

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Detalles Bibliográficos
Autores principales: Delgado-Chaves, Fernando M., Martínez-García, Pedro Manuel, Herrero-Ruiz, Andrés, Gómez-Vela, Francisco, Divina, Federico, Jimeno-González, Silvia, Cortés-Ledesma, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379499/
https://www.ncbi.nlm.nih.gov/pubmed/35983130
http://dx.doi.org/10.1016/j.dib.2022.108499