Cryo‐EM reveals mechanisms of angiotensin I‐converting enzyme allostery and dimerization

Hypertension (high blood pressure) is a major risk factor for cardiovascular disease, which is the leading cause of death worldwide. The somatic isoform of angiotensin I‐converting enzyme (sACE) plays a critical role in blood pressure regulation, and ACE inhibitors are thus widely used to treat hype...

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Detalles Bibliográficos
Autores principales: Lubbe, Lizelle, Sewell, Bryan Trevor, Woodward, Jeremy D, Sturrock, Edward D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379546/
https://www.ncbi.nlm.nih.gov/pubmed/35818993
http://dx.doi.org/10.15252/embj.2021110550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379546/
https://www.ncbi.nlm.nih.gov/pubmed/35818993
http://dx.doi.org/10.15252/embj.2021110550

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