Oxazoline scaffold in synthesis of benzosiloxaboroles and related ring-expanded heterocycles: diverse reactivity, structural peculiarities and antimicrobial activity

Two isomeric benzosiloxaborole derivatives 3a and 5a bearing fluorine and 4,4-dimethyl-2-oxazolin-2-yl substituents attached to the aromatic rings were obtained. Both compounds were prone to hydrolytic cleavage of the oxazoline ring after initial protonation or methylation of the nitrogen atom. The...

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Detalles Bibliográficos
Autores principales: Krajewska, Joanna, Nowicki, Krzysztof, Durka, Krzysztof, Marek-Urban, Paulina H., Wińska, Patrycja, Stępniewski, Tomasz, Woźniak, Krzysztof, Laudy, Agnieszka E., Luliński, Sergiusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379557/
https://www.ncbi.nlm.nih.gov/pubmed/36090419
http://dx.doi.org/10.1039/d2ra03910a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379557/
https://www.ncbi.nlm.nih.gov/pubmed/36090419
http://dx.doi.org/10.1039/d2ra03910a

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