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Multivalent interactions with RNA drive recruitment and dynamics in biomolecular condensates in Xenopus oocytes

RNA localization and biomolecular condensate formation are key biological strategies for organizing the cytoplasm and generating cellular polarity. In Xenopus oocytes, RNAs required for germ layer patterning localize in biomolecular condensates, termed Localization bodies (L-bodies). Here, we have u...

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Detalles Bibliográficos
Autores principales: Cabral, Sarah E., Otis, Jessica P., Mowry, Kimberly L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379569/
https://www.ncbi.nlm.nih.gov/pubmed/35982794
http://dx.doi.org/10.1016/j.isci.2022.104811