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Tripartite motif 38 attenuates cardiac fibrosis after myocardial infarction by suppressing TAK1 activation via TAB2/3 degradation

The role of tripartite motif (TRIM) 38, a ubiquitin E3 ligase regulating various pathophysiological processes, in cardiac fibrosis remains unclear. Here, a model of angiotensin II and myocardial infarction (MI)-induced fibrosis was established to explore its role in cardiac fibrosis and its underlyi...

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Detalles Bibliográficos
Autores principales: Lu, Zhengri, Hao, Chunshu, Qian, Hao, Zhao, Yuanyuan, Bo, Xiangwei, Yao, Yuyu, Ma, Genshan, Chen, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379576/
https://www.ncbi.nlm.nih.gov/pubmed/35982795
http://dx.doi.org/10.1016/j.isci.2022.104780