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Tripartite motif 38 attenuates cardiac fibrosis after myocardial infarction by suppressing TAK1 activation via TAB2/3 degradation
The role of tripartite motif (TRIM) 38, a ubiquitin E3 ligase regulating various pathophysiological processes, in cardiac fibrosis remains unclear. Here, a model of angiotensin II and myocardial infarction (MI)-induced fibrosis was established to explore its role in cardiac fibrosis and its underlyi...
Autores principales: | Lu, Zhengri, Hao, Chunshu, Qian, Hao, Zhao, Yuanyuan, Bo, Xiangwei, Yao, Yuyu, Ma, Genshan, Chen, Lijuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379576/ https://www.ncbi.nlm.nih.gov/pubmed/35982795 http://dx.doi.org/10.1016/j.isci.2022.104780 |
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