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RIOK3 promotes pancreatic ductal adenocarcinoma cell invasion and metastasis by stabilizing FAK

Pancreatic ductal adenocarcinoma (PDAC) is an extremely aggressive cancer, characterized by a high metastatic burden. RIO Kinase 3 (RIOK3) has been shown to promote invasion and metastasis of PDAC by cytoskeleton remodeling, but the exact mechanism is still unknown. In this study, we analyzed transc...

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Detalles Bibliográficos
Autores principales: Xu, Mengyuan, Fang, Lei, Guo, Xin, Qin, Henan, Sun, Rui, Ning, Zhen, Wang, Aman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379581/
https://www.ncbi.nlm.nih.gov/pubmed/35982848
http://dx.doi.org/10.1016/j.heliyon.2022.e10116