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A microengineered Brain-Chip to model neuroinflammation in humans

Species differences in brain and blood–brain barrier (BBB) biology hamper the translation of findings from animal models to humans, impeding the development of therapeutics for brain diseases. Here, we present a human organotypic microphysiological system (MPS) that includes endothelial-like cells,...

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Detalles Bibliográficos
Autores principales: Pediaditakis, Iosif, Kodella, Konstantia R., Manatakis, Dimitris V., Le, Christopher Y., Barthakur, Sonalee, Sorets, Alexander, Gravanis, Achille, Ewart, Lorna, Rubin, Lee L., Manolakos, Elias S., Hinojosa, Christopher D., Karalis, Katia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379671/
https://www.ncbi.nlm.nih.gov/pubmed/35982785
http://dx.doi.org/10.1016/j.isci.2022.104813