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A microengineered Brain-Chip to model neuroinflammation in humans
Species differences in brain and blood–brain barrier (BBB) biology hamper the translation of findings from animal models to humans, impeding the development of therapeutics for brain diseases. Here, we present a human organotypic microphysiological system (MPS) that includes endothelial-like cells,...
Autores principales: | Pediaditakis, Iosif, Kodella, Konstantia R., Manatakis, Dimitris V., Le, Christopher Y., Barthakur, Sonalee, Sorets, Alexander, Gravanis, Achille, Ewart, Lorna, Rubin, Lee L., Manolakos, Elias S., Hinojosa, Christopher D., Karalis, Katia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379671/ https://www.ncbi.nlm.nih.gov/pubmed/35982785 http://dx.doi.org/10.1016/j.isci.2022.104813 |
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