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NIR-light-controlled G-quadruplex hydrogel for synergistically enhancing photodynamic therapy via sustained delivery of metformin and catalase-like activity in breast cancer

Severely hypoxic condition of tumour represents a notable obstacle against the efficiency of photodynamic therapy (PDT). While mitochondria targeted therapy by metformin has been considered as a promising strategy for reducing oxygen consumption in tumours, its low treatment sensitivity, short half-...

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Detalles Bibliográficos
Autores principales: Sun, Yanting, Fang, Kang, Hu, Xiaochun, Yang, Jingxian, Jiang, Zhengyang, Feng, Lei, Li, Ruihao, Rao, Yiming, Shi, Shuo, Dong, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379686/
https://www.ncbi.nlm.nih.gov/pubmed/35983175
http://dx.doi.org/10.1016/j.mtbio.2022.100375