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NIR-light-controlled G-quadruplex hydrogel for synergistically enhancing photodynamic therapy via sustained delivery of metformin and catalase-like activity in breast cancer
Severely hypoxic condition of tumour represents a notable obstacle against the efficiency of photodynamic therapy (PDT). While mitochondria targeted therapy by metformin has been considered as a promising strategy for reducing oxygen consumption in tumours, its low treatment sensitivity, short half-...
Autores principales: | Sun, Yanting, Fang, Kang, Hu, Xiaochun, Yang, Jingxian, Jiang, Zhengyang, Feng, Lei, Li, Ruihao, Rao, Yiming, Shi, Shuo, Dong, Chunyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379686/ https://www.ncbi.nlm.nih.gov/pubmed/35983175 http://dx.doi.org/10.1016/j.mtbio.2022.100375 |
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