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Distinct Cohorts of Aspergillus fumigatus Transcription Factors Are Required for Epithelial Damage Occurring via Contact- or Soluble Effector-Mediated Mechanisms

Damage to the lung epithelium is a unifying feature of disease caused by the saprophytic fungus Aspergillus fumigatus. However, the mechanistic basis and the regulatory control of such damage is poorly characterized. Previous studies have identified A. fumigatus mediated pathogenesis as occurring at...

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Detalles Bibliográficos
Autores principales: Rahman, Sayema, van Rhijn, Norman, Papastamoulis, Panagiotis, Thomson, Darren D., Carter, Zorana, Fortune-Grant, Rachael, Rattray, Magnus, Bromley, Michael John, Bignell, Elaine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379863/
https://www.ncbi.nlm.nih.gov/pubmed/35982778
http://dx.doi.org/10.3389/fcimb.2022.907519