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Chimeric Ligands of Pili and Lectin A Inhibit Tolerance, Persistence, and Virulence Factors of Pseudomonas aeruginosa over a Wide Range of Phenotypes

[Image: see text] Bacteria readily form resilient phenotypes to counter environmental and antibiotic stresses. Here, we demonstrate a class of small molecules that inhibit a wide range of Pseudomonas aeruginosa phenotypes and enable antibiotics to kill previously tolerant bacteria, preventing the tr...

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Detalles Bibliográficos
Autores principales: Patil, Pankaj D., Zheng, Hewen, Burns, Felicia N., Ibanez, Arizza C. S., Jin, Yuchen, Luk, Yan-Yeung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379910/
https://www.ncbi.nlm.nih.gov/pubmed/35658414
http://dx.doi.org/10.1021/acsinfecdis.2c00201