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Multiple time-series expression trajectories imply dynamic functional changes during cellular senescence

Cellular senescence is a dynamic process driven by epigenetic and genetic changes. Although some transcriptomic signatures of senescent cells have been discovered, how these senescence-related signals change over time remains largely unclear. Here, we profiled the transcriptome dynamics of human der...

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Detalles Bibliográficos
Autores principales: Ge, Ming-Xia, Yu, Qin, Li, Gong-Hua, Yang, Li-Qin, He, Yonghan, Li, Ji, Kong, Qing-Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379982/
https://www.ncbi.nlm.nih.gov/pubmed/36016715
http://dx.doi.org/10.1016/j.csbj.2022.08.005