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Molecular and structural basis of actin filament severing by ADF/cofilin

ADF/cofilin’s cooperative binding to actin filament modifies the conformation and alignment of G-actin subunits locally, causing the filament to sever at “boundaries” formed among bare and ADF/cofilin-occupied regions. Analysis of the impact of the ADF/cofilin cluster boundary on the deformation beh...

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Detalles Bibliográficos
Autores principales: Jaswandkar, Sharad V., Katti, Kalpana S., Katti, Dinesh R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9379983/
https://www.ncbi.nlm.nih.gov/pubmed/36016710
http://dx.doi.org/10.1016/j.csbj.2022.07.054