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Convergent Synthesis of Dihydrobenzofurans via Urea Ligand-Enabled Heteroannulation of 2-Bromophenols with 1,3-Dienes

[Image: see text] We disclose a palladium and urea ligand-mediated heteroannulation of 2-bromophenols and 1,3-dienes. This method addresses synthetic challenges present in the palladium-catalyzed heteroannulation of bifunctional reagents and olefins by engaging a diverse scope of coupling partners u...

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Detalles Bibliográficos
Autores principales: Houghtling, Kaitlyn E., Canfield, Amanda M., Paradine, Shauna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380016/
https://www.ncbi.nlm.nih.gov/pubmed/35904546
http://dx.doi.org/10.1021/acs.orglett.2c02301