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HNF4A modulates glucocorticoid action in the liver

The glucocorticoid receptor (GR) is a nuclear receptor critical to the regulation of energy metabolism and inflammation. The actions of GR are dependent on cell type and context. Here, we demonstrate the role of liver lineage-determining factor hepatocyte nuclear factor 4A (HNF4A) in defining liver...

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Detalles Bibliográficos
Autores principales: Hunter, A. Louise, Poolman, Toryn M., Kim, Donghwan, Gonzalez, Frank J., Bechtold, David A., Loudon, Andrew S.I., Iqbal, Mudassar, Ray, David W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380254/
https://www.ncbi.nlm.nih.gov/pubmed/35443180
http://dx.doi.org/10.1016/j.celrep.2022.110697