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HNF4A modulates glucocorticoid action in the liver
The glucocorticoid receptor (GR) is a nuclear receptor critical to the regulation of energy metabolism and inflammation. The actions of GR are dependent on cell type and context. Here, we demonstrate the role of liver lineage-determining factor hepatocyte nuclear factor 4A (HNF4A) in defining liver...
Autores principales: | Hunter, A. Louise, Poolman, Toryn M., Kim, Donghwan, Gonzalez, Frank J., Bechtold, David A., Loudon, Andrew S.I., Iqbal, Mudassar, Ray, David W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380254/ https://www.ncbi.nlm.nih.gov/pubmed/35443180 http://dx.doi.org/10.1016/j.celrep.2022.110697 |
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