Safety and immunogenicity of a typhoid conjugate vaccine among children aged 9 months to 12 years in Malawi: a nested substudy of a double-blind, randomised controlled trial

BACKGROUND: Typhoid fever is a substantial public health problem in Africa, yet there are few clinical trials of typhoid conjugate vaccine (TCV). We assessed immunogenicity and safety of Typbar TCV in Malawi. METHODS: This substudy was nested within a phase 3, double-blind, parallel design, randomis...

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Detalles Bibliográficos
Autores principales: Nampota-Nkomba, Nginache, Nyirenda, Osward M, Khonde, Lameck, Mapemba, Victoria, Mbewe, Maurice, Ndaferankhande, John M, Msuku, Harrison, Masesa, Clemens, Misiri, Theresa, Mwakiseghile, Felistas, Patel, Priyanka D, Patel, Pratiksha, Johnson-Mayo, Ifayet, Pasetti, Marcela F, Heyderman, Robert S, Tracy, J Kathleen, Datta, Shrimati, Liang, Yuanyuan, Neuzil, Kathleen M, Gordon, Melita A, Laurens, Matthew B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380257/
https://www.ncbi.nlm.nih.gov/pubmed/35961356
http://dx.doi.org/10.1016/S2214-109X(22)00275-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380257/
https://www.ncbi.nlm.nih.gov/pubmed/35961356
http://dx.doi.org/10.1016/S2214-109X(22)00275-3

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