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Hormonal regulation of telomerase activity and hTERT expression in steroid-regulated tissues and cancer

Naturally, in somatic cells chromosome ends (telomeres) shorten during each cell division. This process ensures to limit proliferation of somatic cells to avoid malignant proliferation; however, it leads to proliferative senescence. Telomerase contains the reverse transcriptase TERT, which together...

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Detalles Bibliográficos
Autores principales: Taheri, Mohammad, Ghafouri-Fard, Soudeh, Najafi, Sajad, Kallenbach, Julia, Keramatfar, Elmira, Atri Roozbahani, Golnaz, Heidari Horestani, Mehdi, Hussen, Bashdar Mahmud, Baniahmad, Aria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380309/
https://www.ncbi.nlm.nih.gov/pubmed/35974340
http://dx.doi.org/10.1186/s12935-022-02678-9