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Hormonal regulation of telomerase activity and hTERT expression in steroid-regulated tissues and cancer
Naturally, in somatic cells chromosome ends (telomeres) shorten during each cell division. This process ensures to limit proliferation of somatic cells to avoid malignant proliferation; however, it leads to proliferative senescence. Telomerase contains the reverse transcriptase TERT, which together...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380309/ https://www.ncbi.nlm.nih.gov/pubmed/35974340 http://dx.doi.org/10.1186/s12935-022-02678-9 |